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Clostridioides difficile infection (CDI) is one of the most common hospital-acquired (nosocomial) infections and is an increasingly frequent cause of morbidity and mortality among older adult hospitalized patients [ 1-3 ]. CDI is also increasingly diagnosed in younger patients and in the community.

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EVALUATION AND DIAGNOSIS. The history and physical examination in patients presenting with a severely elevated blood pressure (or an acute rise in blood pressure over a previously normal baseline, even if the presenting pressure is <180/120 mmHg) should determine whether any of the following are present [ 1,5 ]: Acute head …Aeromonas species grow at a range of temperatures, although they are isolated with increasing frequency during warmer months (May through October in the Northern hemisphere). Aeromonas species cause a wide spectrum of disease syndromes among warm- and cold-blooded animals, including fish, reptiles, amphibians, mammals, …Indices Commodities Currencies StocksLicensed to: UpToDate Marketing Professional Support Tag : [1102 - 104.224.14.69 - 24B2D16B6F - PR14 - UPT - 20240430-16:47:09UTC] - SM - MD - LG - XL Loading Licensed to: UpToDate Marketing Professional Support Tag : [0602 - 207.46.13.154 - FBF59F1322 - PR14 - UPT - 20240510-02:21:15UTC] - SM - MD - LG - XL Loading

Licensed to: UpToDate Marketing Professional Support Tag : [0602 - 104.224.13.115 - E553BA549D - PR14 - UPT - 20240416-14:45:43UTC] - SM - MD - LG - XL LoadingDisclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or …

Severe sepsis in adults: Rapid overview of emergency management during first hour. Table 1. Securing the airway (if indicated), correcting hypoxemia, and establishing venous access for the early administration of fluids and antibiotics are priorities in the management of patients with sepsis and septic shock [ 3,4 ].Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials.

Mar 8, 2024 · Beta-lactamases are enzymes that open the beta-lactam ring, inactivating the antibiotic. The first plasmid-mediated beta-lactamase in gram-negative bacteria was discovered in Greece in the 1960s. It was named TEM after the patient from whom it was isolated (Temoniera) [ 2 ]. Subsequently, a closely related enzyme was discovered and named TEM-2. Feb 12, 2024 · Although hypokalemia can be transiently induced by the entry of potassium into the cells, most cases result from unreplenished gastrointestinal or urinary losses due, for example, to vomiting, diarrhea, or diuretic therapy [ 1-3 ]. (See "Causes of hypokalemia in adults" .) Potassium replacement is primarily indicated when hypokalemia is due to ... Apr 15, 2024 · Nonsteroidal antiinflammatory drugs (NSAIDs) are medications used to relieve pain and to reduce inflammation. They are some of the most commonly used medications in adults. A variety of NSAIDs are available, including at least 20 in the United States and more elsewhere. Many are available as pills that can be purchased without a prescription ... UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.

Hyponatremia is a common electrolyte disorder that can have serious consequences. Learn how to diagnose and treat SIADH and reset osmostat, two causes of hyponatremia, with evidence-based guidelines.

Mar 15, 2023 · Vaginal yeast infections (also called yeast vaginitis or vaginal candidiasis) are a common problem in women. The most common symptoms are itching and irritation of the vulva and around the opening of the vagina. Vaginal yeast infections usually occur as infrequent episodes, but can recur frequently and may cause chronic persistent symptoms.

UpToDate provides clinical and drug information, patient education, and AI-powered technologies to support better patient care. Learn about the UpToDate suite of solutions, research, integrations, experts, and CME resources.Jan 26, 2024 ... UpToDate · Sign in · Practice Changing UpDates · What's New · UpToDate Pathways · Settings. View Topic. Share. Font Size. Sm...Vaginal yeast infections (also called yeast vaginitis or vaginal candidiasis) are a common problem in women. The most common symptoms are itching and irritation of the vulva and around the opening of the vagina. Vaginal yeast infections usually occur as infrequent episodes, but can recur frequently and may cause chronic persistent symptoms.Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating motor weakness involving ocular, bulbar, limb, and/or respiratory muscles. The weakness is due to an antibody-mediated, immunologic attack directed at proteins in the postsynaptic membrane of the neuromuscular junction (acetylcholine receptors or ...As the condition progresses, most people eventually have inflammation of the joints in the arms or legs. Less commonly, some people have inflammation of the hips and in the upper part of the spine. Joint symptoms — Joint-related symptoms typically include stiffness, pain, redness, warmth to the touch, and swelling.UpToDate personal subscriptions support physicians with evidence-based clinical recommendations. With so much change in the world of patient care, it is clear that access to continuously updated and reliable data is critical for both provider and patient satisfaction. UpToDate® connects you to the most current medical research and findings ...

Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF. This generally includes an acute change in one or more of the following cardinal symptoms: Cough increases in frequency and severity. Sputum production increases in volume and/or changes character. Dyspnea increases. The management of patients with exacerbations of COPD is discussed here. A table to assist with emergency …Myasthenia gravis (MG) is an autoimmune neuromuscular disorder characterized by fluctuating motor weakness involving ocular, bulbar, limb, and/or respiratory muscles. The weakness is due to an antibody-mediated, immunologic attack directed at proteins in the postsynaptic membrane of the neuromuscular junction …The clinical presentation of adrenal insufficiency is variable, depending on whether the onset is acute, leading to adrenal crisis, or chronic, with symptoms that are insidious and vague. The diagnosis of adrenal insufficiency depends upon a critical level of clinical suspicion. Measurements of serum cortisol within three hours after wakening ...UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, …The management of bowel obstruction depends upon the etiology, severity, and location of the obstruction. The goals of initial management are to relieve discomfort and restore normal fluid volume, acid-base balance, and electrolytes. Bowel compromise (ischemia, necrosis, or perforation) and a surgically correctable cause of SBO (eg ...

UpToDate offers clinical, drug, and patient content to support health professionals wherever care takes place. Learn about subscription options, expert editorial content, access at the point of care, and improved health outcomes with UpToDate.Apr 5, 2024 · INTRODUCTION. —. Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis.

Remember Dollar Shave Club? It's the service that delivers fresh razors to your doorstep, monthly, for a fraction of the cost of the grocery-store equivalent. They had a killer vir...Blood pressure is reported as the systolic pressure over diastolic pressure (eg, 120/70 or "120 over 70"). Untreated high blood pressure increases the strain on the heart and arteries, eventually causing organ damage. High blood pressure increases the risk of heart failure, heart attack (myocardial infarction), stroke, and kidney failure.UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.Mar 28, 2024 ... Outline · Suboptimal response · - Adjunctive CBT · - Pharmacologic management · No response to SRI treatment · Partial response ...The four essential components of asthma management are patient education, minimizing exposure to asthma triggers, monitoring for changes in symptoms or lung function, and pharmacologic therapy. This overview topic presents the goals and components of asthma management. It is applicable to both children and adults.Dec 11, 2023 · Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials. The pericardium is a fibroelastic sac made up of visceral and parietal layers separated by a (potential) space, the pericardial cavity. In healthy individuals, the pericardial cavity contains 15 to 50 mL of an ultrafiltrate of plasma. Diseases of the pericardium present clinically in one of several ways: Acute and recurrent pericarditis.In-application and email messages will remind you to log in to UpToDate from your organization's network to re-verify your affiliation. If you are no longer affiliated with the providing institution: You can still access UpToDate if you are no longer affiliated with your institution by purchasing an individual subscription. Click here to subscribe.Therapy for hyperkalemia due to potassium retention is ultimately aimed at inducing potassium loss [ 1-3 ]. In some cases, the primary problem is movement of potassium out of the cells, even though the total body potassium may be reduced. Redistributive hyperkalemia most commonly occurs in uncontrolled hyperglycemia (eg, …

Trusted for more than 30 years, UpToDate® is the clinical decision support resource that provides over 2 million medical professionals worldwide with the latest evidence-based information available across 25 specialties. With the ever-increasing complexity of diseases, medicine, and clinical practice in today's world, UpToDate is dedicated to ...

Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odor, pruritus, and/or discomfort. The initial evaluation typically consists of a history, physical examination, and tests for specific infections, including sexually ...

The clinical approach to S. aureus bacteremia consists of careful history and physical examination, infectious disease consultation, and diagnostic evaluation including echocardiography and additional imaging as needed. History and physical examination. History – A careful history and physical examination is essential.Clostridioides difficile infection (CDI) is one of the most common hospital-acquired (nosocomial) infections and is an increasingly frequent cause of morbidity and mortality among older adult hospitalized patients [ 1-3 ]. CDI is also increasingly diagnosed in younger patients and in the community.UpToDate offers clinical, drug, patient and member content to support health professionals wherever care takes place. Learn about the UpToDate suite, its expert editorial content, access options, research studies, CME, and innovation in AI.In-application and email messages will remind you to log in to UpToDate from your organization's network to re-verify your affiliation. If you are no longer affiliated with the providing institution: You can still access UpToDate if you are no longer affiliated with your institution by purchasing an individual subscription. Click here to subscribe.Previously unidentified systemic and extrapulmonary manifestations of disease may also be present in this group. These may include fatigue, malaise, weight loss, exertional dyspnea, skin rashes, peripheral lymphadenopathy, nephrolithiasis, uveitis, palpitations, and syncope and Bell palsy, among others.Mar 28, 2024 · Generalized anxiety disorder (GAD) is characterized by excessive worry and anxiety that are difficult to control, cause significant distress and impairment, and occur on more days than not for at least six months [ 1 ]. GAD is a relatively common disorder, most often with an adult onset and chronic course [ 2-6 ]. Use the resource trusted by healthcare practitioners worldwide. Patients and their caregivers can learn more about a medical condition and explore treatment options using UpToDate, the same resource trusted by more than 2 million clinicians around the world. After you read the information in UpToDate, you will have the tools and the confidence ...Acute pulmonary embolism (PE) is a common and sometimes fatal disease with a variable clinical presentation. It is critical that therapy be administered in a timely fashion [ 1-5 ]. The treatment, prognosis, and follow-up of patients with acute PE are reviewed here. The epidemiology, pathophysiology, clinical presentation, and diagnosis …Licensed to: UpToDate Marketing Professional Support Tag : [0602 - 104.224.13.115 - E553BA549D - PR14 - UPT - 20240416-14:45:43UTC] - SM - MD - LG - XL LoadingDiarrheal disease is one of the top ten leading causes of death worldwide and is a particular concern for children younger than five years old in resource-limited settings [ 1 ]. Among adults in resource-abundant settings, diarrhea is often a "nuisance disease" in the healthy individual. Most cases of acute diarrhea in adults are of infectious ...Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username.May 6, 2022 · The signs and symptoms of anemia include paleness, weakness, and fatigue. Impaired kidney function — The excess proteins and high blood calcium levels associated with MM can damage the kidneys. Kidney function is abnormal at diagnosis in about half of individuals with multiple myeloma.

UpToDate. With powerful and practical knowledge at your fingertips, UpToDate® is the only clinical decision support resource associated with improved patient outcomes. Purchase personal or group subscriptions for up to 19. Purchase UpToDate Online.Management of insomnia requires a stepwise approach, beginning with attempts to eliminate, or at least minimize, the multiple contributing factors and comorbid illnesses that can interfere with optimal sleep. Insomnia often responds only partially to treatment of sleep-impairing influences, however, and many patients require treatment …UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, Obstetrics, Gynecology, and Women ...Instagram:https://instagram. pffcu philadelphiagreat southern bankquick photolas vegas to san jose Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.Helicobacter pylori, also known as H. pylori, is a bacterium that is commonly found in the stomach. It is present in approximately one-half of the world's population. The vast majority of people infected with H. pylori has no symptoms and will never develop problems. However, H. pylori is capable of causing a number of digestive problems ... watch bombshellnick shoes Other manifestations include lower abdominal pain and cramping, low-grade fever, nausea, and anorexia [ 2,5 ]. Diarrhea may be associated with mucus or occult blood, but melena or hematochezia are rare. Fever is associated with CDI in about 15 percent of cases; temperature >38.5°C may occur in the setting of nonsevere or severe CDI.The preventive treatment of episodic migraine headache in adults is reviewed here. The clinical features and management of chronic migraine (defined as ≥15 headache days per month) are discussed separately. (See "Chronic migraine" .) Other aspects of migraine are reviewed elsewhere. take off safe mode Shingles, also known as herpes zoster, is a painful rash caused by varicella-zoster virus (the same virus that causes chickenpox). After a person has had chickenpox, the virus continues to reside in the body, causing no symptoms. Later in life, it can become active again, causing the shingles rash. The term "shingles" comes from the Latin word ...